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Some prefer injecting near the injury site for localized effects, while others use subcutaneous abdominal injections for systemic distribution

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Main conclusions: GHK-Cu acts via 6 main mechanisms (described above) The endogenous decrease with age is documented in various populations Topical applications in dermatology are the best validated Antimicrobial effect , GHK-Cu also has a mild antibacterial profile The safety profile is excellent, no toxic doses were reached in animal studies Why it matters: This review became a reference source for the dermatological and cosmetic research community

Funding This work was supported by National Natural Science Foundation of China (82102431 to J.Y.)

If you take a high dose (1,000 mcg), your body absorbs only about 1% of it (NIH-a, 2021)